Disease table of PULMONARY FIBROSIS, IDIOPATHIC OMIM ID: 178500

Gene-disease associations table

Gene	Associated with PULMONARY FIBROSIS, IDIOPATHIC in	Link to HGNC	Cytogenetic band	Number of associated diseases	Associated diseases
TERT	ClinVar	HGNC link	5p15.33	5	PS127550, 601626, 178500, PS155600, PS614742
TERC	ClinVar	HGNC link	3q26.2	3	PS614742, 178500, PS127550
SFTPA2	ClinVar, OMIM, HUMSAVAR	HGNC link	10q22.3	1	178500
SFTPA1	OMIM	HGNC link	10q22.3	1	178500
MUC5B	ClinVar, OMIM	HGNC link	11p15.5	1	178500
RTEL1	ClinVar	HGNC link	20q13.33	3	PS614742, 178500, PS127550

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD

Common tandem group	Number of genes in this tandem group associated to this disease	Genes in this tandem group associated to this disease
Group 469	2	SFTPA1, SFTPA2

Cytogenetic band analysis

By sub-band

Shared sub_band	Number of genes associated with the disease	Genes associated with the disease
10q22.3	2	SFTPA1, SFTPA2

By band

Shared band	Number of genes associated with the disease	Genes associated with the disease
10q22	2	SFTPA1, SFTPA2

By region

Shared region	Number of genes associated with the disease	Genes associated with the disease
10q2	2	SFTPA1, SFTPA2

By arm

Shared arm	Number of genes associated with the disease	Genes associated with the disease
10q	2	SFTPA1, SFTPA2

By chromosome

Shared chromosome	Number of genes associated with the disease	Genes associated with the disease
10	2	SFTPA1, SFTPA2

Transcription Factors (TF) annotation from TRRUST

TF	associated to this disease	# regulated genes	Regulated genes	# regulated genes associated with this disease	Regulated genes associated with this disease
NFKB1	NO	306	NRF1, VWF, FTH1, PGLYRP2, CDK4, RGS4, IFNG, MMP2, DCST1, AGT, THBD, EGFR, GDNF, CCL4, NCAM1, VEGFA, CR2, CFI, TP53, FOXO3, CYP19A1, BGN, LPL, CXCL12, ELF3, PTHLH, HOXA9, IRF7, TNC, AGER, EDN1, HBEGF, SFTPA1, SAA1, TSLP, GSK3A, IFNB1, GKN2, TRAF2, PLA2G2A, F3, IL10, LIPE, FAF1, IL17A, CEACAM1, AKT1, KLK3, IL1RN, GSTP1, E2F1, CCR5, TAPBP, ADORA2A, CXCL1, PTPN6, MMP3, PIGR, ERAP1, YY1, OLFM4, DEFB4A, CCL2, CD28, SQSTM1, TERT, IL4, NAMPT, BACE1, JUNB, SLC9A2, FASLG, ALOX5, BCL2L1, CD83, TLR3, CCL22, PLIN1, CDKN1A, BIRC3, CSF2, CFLAR, TFPI2, MYB, IL18, SERPINB1, MUC17, TNFRSF10A, PTGFR, TFF3, PTAFR, PTGS2, COX1, SERPINA3, ITGAX, CCND2, MCL1, TLR7, POU2F2, REPS2, CD3G, TFF1, B2M, PLAU, TNF, FOXP3, HDAC7, MUC5B, CCR2, FIGF, HSD11B2, CCL13, IFNA1, NOX5, MAT2A, COL7A1, HMOX1, ADORA1, TNFSF10, AR, COL2A1, TAP1, IL1B, CD74, CD38, MUC5AC, MUC2, TIMP1, CCL19, FGF8, PDK4, CCL20, STK39, CYP3A7, MMP9, GATA3, IRF4, CD58, HES1, PLAUR, SP4, NFKB1, MMP1, NOX4, BDKRB1, CASP3, CYP1A1, PSMB9, PTEN, HPSE, CCNB1, CD40, NOS3, PTGDS, UPP1, HIF1A, TNFRSF9, CD80, TNFSF13B, IL23A, TNFAIP3, TNFSF14, IL12A, TRPC1, CYP2E1, OPRM1, HLA-F, AMH, XIAP, MADCAM1, HYAL1, A2M, CCL11, TBX21, ICAM1, BCL2L11, CHUK, TAP2, IL2RA, CTCF, ABCB1, GSK3B, CCND1, KLF5, CCR7, CCK, DCST2, MMP14, IL17C, FBP1, OPTN, IL1A, LTC4S, COL1A2, NOS1, WT1, BIRC5, PPIG, PTGES, CREB3, CXCL2, CRP, KDM2A, BCL2A1, BRCA2, IKBKB, GFAP, PSMB10, PROX1, COL1A1, TNIP3, NFKBIZ, TLR2, S100A6, DRD2, CXCL8, CD86, TRAF1, PTPN13, CSNK2A1, CARD8, CXCL10, IL6, CFTR, CASP9, ABCG2, BMP2, CRMP1, IL2, IRF1, SOD2, IER3, NFKBIA, FN1, SERPINE1, MICA, TBP, CXCR2, BHMT, NCOR1, SNAI1, BAX, NPPB, CTSB, F8, IL12B, IGF2BP1, LCN2, NOLC1, CD40LG, SELE, NOD2, CCL5, FAS, ALOX5AP, OLR1, CXCR4, SDC1, FLT4, NCOR2, AKT2, CDH1, TGFB1, CCL3, IGF2BP2, HDAC1, SP1, PDE7A, ADORA3, CRHR1, BCL3, MIF, CXCL5, TNFRSF10B, HAX1, CYP27B1, NLRP2, FGF7, PTGER4, TNFRSF13C, CARM1, EBI3, VCAM1, ERAP2, MYC, CSF1, EPCAM, SLC25A27, NOS2, RIPK2, EGR1, BTG2, BCL2, ABCA1, CD69, BIRC2, CCR3, IL21, GCLC, MMP13, GRIN1, SP3, RRM2B, STAT4, TF, MUC6	3	SFTPA1, MUC5B, TERT
RELA	NO	302	NRF1, OXTR, FTH1, CDK4, UPP1, IFNG, MMP2, DCST1, AGT, FLT4, EGFR, CCL4, NCAM1, VEGFA, CR2, CFI, TP53, FOXO3, CYP19A1, BGN, LPL, CXCL12, ELF3, PTHLH, IRF7, TNC, AGER, EDN1, SFTPA1, IGF2BP2, PPARA, SAA1, TSLP, GSK3A, IFNB1, GKN2, PLA2G2A, F3, IL10, KLK3, MMP12, IL17A, NR4A1, CEACAM1, AKT1, EPAS1, IL1RN, BAX, TRIB3, E2F1, PCK2, CXCL1, PTPN6, MMP3, CDK6, PIGR, ERAP1, YY1, OLFM4, IL18, LIPE, CD28, MMP9, TERT, IL4, NAMPT, BACE1, JUNB, CCR2, FASLG, ALOX5, BCL2L1, CCL11, PGR, GTF2B, CCL22, PLIN1, AKT2, BIRC3, HBEGF, CCL2, SERPINB1, MUC17, BAD, FGF7, PTGFR, TFF3, PTAFR, PTGS2, COX1, SERPINA3, ITGAX, CCND2, MCL1, TLR7, POU2F2, REPS2, TF, TFF1, SLC9A2, PLAU, TNF, FOXP3, HDAC7, MUC5B, NCOR1, FIGF, CYP3A4, SP1, CCL13, IFNA1, NOX5, MAT2A, COL7A1, HMOX1, ADORA1, TNFSF10, AR, CCR5, COL2A1, TAP1, IL1B, CD74, CD38, MUC5AC, GSTP1, MUC2, TIMP1, CCL19, CXCR4, FGF8, PDK4, CCL20, STK39, CYP3A7, GATA3, IRF4, CD58, HES1, PLAUR, SP4, NFKB1, MMP1, NOX4, BDKRB1, CASP3, CYP1A1, PTEN, HPSE, CCNB1, CD40, NOS3, ABCA1, PPARD, HIF1A, TNFRSF9, CD80, KDM2A, IL23A, TNFAIP3, TNFSF14, IL12A, TRPC1, CYP2E1, RGS4, ADORA2A, AMH, XIAP, MADCAM1, HYAL1, CFLAR, TBX21, ICAM1, BCL2L11, CHUK, TAP2, IL2RA, TLR3, ABCB1, IL17C, CCND1, KLF5, CCR7, CCK, DCST2, MMP14, FBP1, OPTN, IL1A, LTC4S, COL1A2, NOS1, WT1, BIRC5, PPIG, PTGES, THBD, CREB3, VWF, CXCL2, CRP, HLA-A, BCL2A1, BRCA2, IKBKB, GFAP, TWIST1, PSMB10, PROX1, COL1A1, TNIP3, NFKBIZ, TLR2, TNFRSF10A, S100A6, DRD2, CXCL8, BTG2, TRAF1, PTPN13, CD83, CSNK2A1, CARD8, CXCL10, CDKN1A, IL6, CFTR, CASP9, SIRT1, BMP2, IL2, IRF1, SOD2, IER3, NFKBIA, FN1, SERPINE1, MICA, TBP, CXCR2, BHMT, ABCG2, SNAI1, NOS2, PSMB9, CTSB, HSD11B2, F8, IL12B, IGF2BP1, LCN2, NOLC1, CD40LG, SELE, CCL5, FAS, ALOX5AP, OLR1, VCAM1, SDC1, SAA2, NCOR2, DEFB4A, CDH1, TRAF2, CCL3, GNRH2, HDAC1, TAPBP, CSF2, ADORA3, CRHR1, BCL3, MIF, CXCL5, TNFRSF10B, CYP27B1, NLRP2, FAF1, PTGER4, TNFRSF13C, CARM1, EBI3, ERAP2, CSF1, EPCAM, SLC25A27, RIPK2, EGR1, CD86, BCL2, CD69, BIRC2, CCR3, NPPB, GCLC, MMP13, GRIN1, SP3, MYC, STAT4, MUC6	3	SFTPA1, MUC5B, TERT

regulated gene	associated to this disease	# TFs	TFs
TERT	YES	30	CTCF, MZF1, ETS2, MXD1, USF2, SP1, ID2, TAL1, SMAD3, DNMT1, E2F1, WT1, ESR2, HDAC1, JUN, TP53, RELA, NFKB1, TP73, ETS1, HIF1A, STAT3, MEN1, NFATC2, FLI1, USF1, ESR1, MYC, PITX1, MYCN
SFTPA1	YES	3	NFKB1, NKX2-1, RELA
MUC5B	YES	2	NFKB1, RELA

Interactions from BIOGRID - physical

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
TERT	TERC	Yes	3	RUVBL1, RUVBL2, DKC1
TERT	RTEL1	No	1	XRCC5

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic

Interactions from STRING

Gene1	Gene2	Direct Interaction	Interaction mode	Number of shared interactors	Shared genes in interaction
TERT	SFTPA2	No	-	1	EGFR
TERT	SFTPA1	No	-	1	EGFR
TERT	MUC5B	No	-	1	EGFR
SFTPA2	SFTPA1	Yes	reaction	2	EGFR, FOXA1
SFTPA2	MUC5B	No	-	1	EGFR
SFTPA1	MUC5B	No	-	1	EGFR

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM

Interactions from CENSUS

Interactions from PDB

Interactions from manually curated literature

KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG term	KEGG term ID	IC	Number of genes with the same term	Genes
Pertussis	hsa05133	6.46	2	SFTPA2, SFTPA1
Phagosome	hsa04145	5.27	2	SFTPA2, SFTPA1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
Pertussis (hsa05133)	-	6.46	0.035	SFTPA2, SFTPA1
Phagosome (hsa04145)	-	5.27	0.047	SFTPA2, SFTPA1

REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME term	REACTOME term ID	IC	Number of genes with the same term	Genes
Toll-Like Receptors Cascades	R-HSA-168898	5.91	2	SFTPA2, SFTPA1
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	6.51	2	SFTPA2, SFTPA1
Immune System	R-HSA-168256	2.37	2	SFTPA2, SFTPA1
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	6.51	2	SFTPA2, SFTPA1
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	6.11	2	SFTPA2, SFTPA1
Cell-Cell communication	R-HSA-1500931	5.87	2	SFTPA2, SFTPA1
Innate Immune System	R-HSA-168249	3.17	2	SFTPA2, SFTPA1
Signal regulatory protein (SIRP) family interactions	R-HSA-391160	8.98	2	SFTPA2, SFTPA1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
Signal regulatory protein (SIRP) family interactions (R-HSA-391160)	-	8.98	0.001	SFTPA2, SFTPA1
Toll Like Receptor 2 (TLR2) Cascade (R-HSA-181438)	-	6.51	0.029	SFTPA2, SFTPA1
Toll Like Receptor TLR1:TLR2 Cascade (R-HSA-168179)	-	6.51	0.029	SFTPA2, SFTPA1

GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GO	IC	Number of genes with the same GO	Genes
binding (GO:0005488)	0.18	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
protein binding (GO:0005515)	0.46	4	RTEL1, SFTPA1, MUC5B, TERT
cation binding (GO:0043169)	1.4	2	RTEL1, TERT
organic cyclic compound binding (GO:0097159)	1.05	2	RTEL1, TERT
carbohydrate binding (GO:0030246)	4.17	2	SFTPA2, SFTPA1
ion binding (GO:0043167)	1.36	2	RTEL1, TERT
catalytic activity (GO:0003824)	1.05	2	RTEL1, TERT
nucleic acid binding (GO:0003676)	1.44	2	RTEL1, TERT
DNA binding (GO:0003677)	1.92	2	RTEL1, TERT
metal ion binding (GO:0046872)	1.41	2	RTEL1, TERT
heterocyclic compound binding (GO:1901363)	1.06	2	RTEL1, TERT

GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
primary metabolic process (GO:0044238)	0.69	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cellular macromolecule metabolic process (GO:0044260)	0.93	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cellular process (GO:0009987)	0.26	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cellular metabolic process (GO:0044237)	0.69	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
macromolecule metabolic process (GO:0043170)	0.83	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
organic substance metabolic process (GO:0071704)	0.63	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
metabolic process (GO:0008152)	0.58	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
single-organism process (GO:0044699)	0.48	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cellular protein metabolic process (GO:0044267)	1.63	3	SFTPA2, MUC5B, SFTPA1
protein metabolic process (GO:0019538)	1.45	3	SFTPA2, MUC5B, SFTPA1
response to stimulus (GO:0050896)	1.22	3	RTEL1, MUC5B, TERT
regulation of cellular process (GO:0050794)	0.5	3	RTEL1, MUC5B, TERT
response to stress (GO:0006950)	1.8	3	RTEL1, MUC5B, TERT
biological regulation (GO:0065007)	0.39	3	RTEL1, MUC5B, TERT
single-organism cellular process (GO:0044763)	0.65	3	RTEL1, MUC5B, TERT
regulation of biological process (GO:0050789)	0.45	3	RTEL1, MUC5B, TERT
negative regulation of metabolic process (GO:0009892)	1.93	2	RTEL1, TERT
positive regulation of metabolic process (GO:0009893)	1.74	2	RTEL1, TERT
regulation of metabolic process (GO:0019222)	1.02	2	RTEL1, TERT
anatomical structure homeostasis (GO:0060249)	4.25	2	RTEL1, TERT
negative regulation of response to stimulus (GO:0048585)	2.52	2	RTEL1, TERT
negative regulation of cellular metabolic process (GO:0031324)	2.01	2	RTEL1, TERT
regulation of response to stimulus (GO:0048583)	1.54	2	RTEL1, TERT
nucleic acid metabolic process (GO:0090304)	1.46	2	RTEL1, TERT
cellular biosynthetic process (GO:0044249)	1.37	2	RTEL1, TERT
cellular nitrogen compound metabolic process (GO:0034641)	1.22	2	RTEL1, TERT
nitrogen compound metabolic process (GO:0006807)	1.13	2	RTEL1, TERT
cellular macromolecule biosynthetic process (GO:0034645)	1.66	2	RTEL1, TERT
organic cyclic compound metabolic process (GO:1901360)	1.26	2	RTEL1, TERT
regulation of primary metabolic process (GO:0080090)	1.08	2	RTEL1, TERT
telomere maintenance (GO:0000723)	5.37	2	RTEL1, TERT
organic substance biosynthetic process (GO:1901576)	1.34	2	RTEL1, TERT
cellular response to stimulus (GO:0051716)	1.97	2	RTEL1, TERT
negative regulation of macromolecule metabolic process (GO:0010605)	2.01	2	RTEL1, TERT
positive regulation of macromolecule metabolic process (GO:0010604)	1.81	2	RTEL1, TERT
cellular component organization (GO:0016043)	1.24	2	RTEL1, TERT
regulation of nucleobase-containing compound metabolic process (GO:0019219)	1.43	2	RTEL1, TERT
cellular component organization or biogenesis (GO:0071840)	1.22	2	RTEL1, TERT
positive regulation of biological process (GO:0048518)	1.2	2	RTEL1, TERT
negative regulation of biological process (GO:0048519)	1.33	2	RTEL1, TERT
regulation of biological quality (GO:0065008)	1.68	2	RTEL1, TERT
positive regulation of cellular metabolic process (GO:0031325)	1.81	2	RTEL1, TERT
multicellular organismal process (GO:0032501)	1.45	2	SFTPA2, SFTPA1
positive regulation of nucleobase-containing compound metabolic process (GO:0045935)	2.35	2	RTEL1, TERT
negative regulation of nucleobase-containing compound metabolic process (GO:0045934)	2.55	2	RTEL1, TERT
nucleobase-containing compound metabolic process (GO:0006139)	1.35	2	RTEL1, TERT
regulation of macromolecule metabolic process (GO:0060255)	1.08	2	RTEL1, TERT
regulation of cellular metabolic process (GO:0031323)	1.07	2	RTEL1, TERT
respiratory gaseous exchange (GO:0007585)	5.86	2	SFTPA2, SFTPA1
cellular aromatic compound metabolic process (GO:0006725)	1.3	2	RTEL1, TERT
single-organism metabolic process (GO:0044710)	1.63	2	RTEL1, MUC5B
biosynthetic process (GO:0009058)	1.32	2	RTEL1, TERT
macromolecule biosynthetic process (GO:0009059)	1.61	2	RTEL1, TERT
regulation of nitrogen compound metabolic process (GO:0051171)	1.36	2	RTEL1, TERT
negative regulation of nitrogen compound metabolic process (GO:0051172)	2.47	2	RTEL1, TERT
positive regulation of nitrogen compound metabolic process (GO:0051173)	2.29	2	RTEL1, TERT
establishment of localization (GO:0051234)	1.48	2	SFTPA1, TERT
localization (GO:0051179)	1.4	2	SFTPA1, TERT
heterocycle metabolic process (GO:0046483)	1.31	2	RTEL1, TERT
organelle organization (GO:0006996)	2.02	2	RTEL1, TERT
homeostatic process (GO:0042592)	2.61	2	RTEL1, TERT
chromosome organization (GO:0051276)	3.79	2	RTEL1, TERT
single-multicellular organism process (GO:0044707)	1.78	2	SFTPA2, SFTPA1
regulation of response to stress (GO:0080134)	2.53	2	RTEL1, TERT
regulation of cellular response to stress (GO:0080135)	3.4	2	RTEL1, TERT
telomere organization (GO:0032200)	5.33	2	RTEL1, TERT
cellular response to stress (GO:0033554)	2.51	2	RTEL1, TERT
DNA metabolic process (GO:0006259)	3.09	2	RTEL1, TERT
negative regulation of cellular process (GO:0048523)	1.41	2	RTEL1, TERT
positive regulation of cellular process (GO:0048522)	1.3	2	RTEL1, TERT

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
telomere maintenance (GO:0000723)	-	5.37	0.025	RTEL1, TERT
respiratory gaseous exchange (GO:0007585)	-	5.86	0.013	SFTPA2, SFTPA1
telomere organization (GO:0032200)	-	5.33	0.026	RTEL1, TERT

GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
intracellular membrane-bounded organelle (GO:0043231)	0.6	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cell part (GO:0044464)	0.11	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
intracellular organelle part (GO:0044446)	0.81	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
intracellular organelle (GO:0043229)	0.51	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
intracellular part (GO:0044424)	0.28	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
membrane-bounded organelle (GO:0043227)	0.47	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
organelle (GO:0043226)	0.4	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
organelle part (GO:0044422)	0.79	5	RTEL1, SFTPA2, MUC5B, SFTPA1, TERT
cytoplasmic part (GO:0044444)	0.82	4	SFTPA2, MUC5B, SFTPA1, TERT
protein complex (GO:0043234)	1.51	3	SFTPA2, SFTPA1, TERT
macromolecular complex (GO:0032991)	1.35	3	SFTPA2, SFTPA1, TERT
vesicle (GO:0031982)	1.64	3	SFTPA2, MUC5B, SFTPA1
membrane-bounded vesicle (GO:0031988)	1.71	3	SFTPA2, MUC5B, SFTPA1
extracellular region (GO:0005576)	2.18	3	SFTPA2, MUC5B, SFTPA1
extracellular region part (GO:0044421)	1.57	3	SFTPA2, MUC5B, SFTPA1
extracellular space (GO:0005615)	2.63	3	SFTPA2, MUC5B, SFTPA1
nucleoplasm (GO:0005654)	1.89	2	RTEL1, TERT
collagen trimer (GO:0005581)	5.21	2	SFTPA2, SFTPA1
secretory vesicle (GO:0099503)	4.0	2	SFTPA2, SFTPA1
cytoplasmic, membrane-bounded vesicle (GO:0016023)	3.12	2	SFTPA2, SFTPA1
cytoplasmic vesicle (GO:0031410)	2.87	2	SFTPA2, SFTPA1
nucleus (GO:0005634)	1.07	2	RTEL1, TERT
membrane (GO:0016020)	0.68	2	SFTPA2, SFTPA1
extracellular matrix (GO:0031012)	3.81	2	SFTPA2, SFTPA1
endocytic vesicle (GO:0030139)	5.04	2	SFTPA2, SFTPA1
endoplasmic reticulum part (GO:0044432)	2.73	2	SFTPA2, SFTPA1
clathrin-coated endocytic vesicle (GO:0045334)	6.97	2	SFTPA2, SFTPA1
endoplasmic reticulum membrane (GO:0005789)	2.95	2	SFTPA2, SFTPA1
intracellular vesicle (GO:0097708)	2.86	2	SFTPA2, SFTPA1
membrane part (GO:0044425)	0.95	2	SFTPA2, SFTPA1
secretory granule (GO:0030141)	4.34	2	SFTPA2, SFTPA1
nuclear part (GO:0044428)	1.55	2	RTEL1, TERT
lamellar body (GO:0042599)	6.86	2	SFTPA2, SFTPA1
coated vesicle (GO:0030135)	4.94	2	SFTPA2, SFTPA1
proteinaceous extracellular matrix (GO:0005578)	4.01	2	SFTPA2, SFTPA1
clathrin-coated vesicle (GO:0030136)	5.26	2	SFTPA2, SFTPA1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
collagen trimer (GO:0005581)	-	5.21	0.01	SFTPA2, SFTPA1