Disease table of NEONATAL INFLAMMATORY SKIN AND BOWEL DISEASE OMIM ID: PS614328

Gene-disease associations table

GeneAssociated with NEONATAL INFLAMMATORY SKIN AND BOWEL DISEASE inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
EGFRClinVar, OMIM, HUMSAVARHGNC link7p11.23275355, 211980, PS614328
ADAM17OMIMHGNC link2p25.11PS614328

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
SP1NO460ITGB3, KRT14, CDK4, UGCG, PGR, GAST, PSIP1, ITGA5, PTHLH, ITGB2, CD44, HLA-G, LTF, IGFBP4, NF1, ACVRL1, GSTP1, CYP2F1, CA9, MMRN1, HSD17B2, STK11, FGFR3, CD28, UGT1A4, FASLG, DNASE2, KRT19, SLC39A1, ALOX5, PDGFB, PTGS2, CYP7A1, TNF, TPMT, HSD11B2, FMR1, CHI3L1, PCK1, DMRT1, RARA, RASSF1, CYP3A7, BRD7, CYP17A1, LPL, CXADR, PADI3, ABCA1, NR5A1, COL11A2, IRF5, XIAP, BACE1, STAR, TBX21, BSG, APP, MDM2, COMP, ALOX12, CHRNB4, SNAP25, MTA1, CCK, DDB2, CIC, ACAN, KIT, MAT2A, SERPINB5, CDH2, ICAM1, SLC29A1, USP7, SLC5A8, HTR1A, REST, IGF2, APOC3, APAF1, ABCG2, IFNGR1, CRMP1, SLC7A5, PDGFC, HNF4A, ATP2C1, MICA, EAPP, TNFRSF10B, KRT5, MACROD1, ERVW-1, CD151, ELF4, MMP28, POLD2, DNMT1, MAOB, CBS, E2F1, KCNQ3, COL18A1, HIST2H4A, RPS3A, IL10, C4A, CYP3A5, ST6GAL1, CD99, BCL2, SLC15A1, IL6, ADAM10, KRT16, POLE2, MUC6, CBFB, ACO1, DCK, CAV1, MIF, DNMT3A, HMGA2, PDIA2, B4GALT1, GJA1, PPL, SLC13A4, AGTR1, PTGIR, CETP, SLC2A2, CYP27A1, F2R, BLMH, ADIPOQ, CENPH, OPRM1, BAG2, MPO, WRN, CDK6, PTTG1, YY1, CD2AP, TBXA2R, TGM4, PRSS50, HSD17B11, HCN2, MYCN, F3, ID4, CDKN1A, SLC5A1, SERPINE1, C1QBP, SOX3, EGR1, TF, RETN, SYP, RORA, NDUFV1, C4B, SNAPC1, TGFBR2, MME, GATA3, DPYSL2, CXCL14, SPRY2, ABCB8, COX4I1, SCTR, UGDH, HBEGF, PLAT, FOS, XPC, MUC5AC, HYAL1, BRCA1, NOS1, KCTD11, HCN4, ASPN, OXTR, COL1A1, TLR2, ALOX15B, ITGAV, IL5, SLC9A2, SIRT1, FGL2, KLF8, KCNQ2, UGT2B15, FOXM1, TEC, CHST4, TINF2, SLC19A3, KIF2C, ADAM23, PTGES, DNMT3B, GCLC, THBD, GFER, ADRBK1, TGFB1, SLC25A20, TK1, PRM1, CXCL1, APOE, PDE6A, TICAM1, KCNH2, TERF2, CENPW, NFKB1, ITGA2, PCYT1A, SIGIRR, IRS2, SP3, GIPR, SCNN1B, PTN, PTEN, NDUFV2, INSR, AGT, ME1, ATP2A2, HAS2, CYP19A1, HTT, MAT2B, PRNP, MNDA, SLC9A3, ADAM17, BAX, SLC3A2, UTRN, SPN, PAX6, SMARCA1, IL2, CREM, MMP9, ENG, CHGA, MUC4, ESR1, AHR, ATM, NFKB2, COL7A1, CD97, EPO, TFPI2, POR, DRG2, ELMO3, CAT, CYP3A4, LOXL4, BDKRB1, WAS, PNOC, LDHC, ADH6, CDC42BPG, NKX2-1, CYP1B1, TAF7, PLAUR, MMP2, MMP11, APLNR, UBC, GM2A, FGFR1, PLAA, TIMP1, TNFSF14, PTK6, KISS1, CDKN2B, COL2A1, BTK, ITGAX, HBZ, CREB1, MMP14, MICB, LEP, FOLR1, ATP2A3, SNRPN, ADA, PSEN1, SPP1, TNNI3, NOL7, VEGFA, CSNK2A1, VAMP2, NQO2, LOR, EPOR, HSD3B1, ISG20, MET, F10, CD1D, FBLN1, APLP1, CCL5, FAS, ERBB2, COPS5, MYBL1, RECQL4, CD83, SOD1, HOXB7, WIF1, SLC39A8, CES1, IL5RA, APEX1, ITGAD, TNC, KDR, CLDN3, NR4A1, MYC, RELA, RECK, PGLYRP2, LRP5, MYBL2, ADRA2B, VIM, EGFR, GDA, SOD2, FES, LDHA, CD14, AMACR, IGFBP1, SLC19A1, IMPDH2, PDE6B, LCAT, PPP2R2B, FBN1, CERS2, EPAS1, KLK3, FLNA, CCL2, HMGA1, BACE2, EDNRB, FABP6, HPR, IGFBP3, PON1, APOA1, NPY, B4GALT5, FXR2, CCND2, STARD3, IL2RB, DDB1, SQSTM1, TERT, HGF, TNFSF10, KRT18, TYMP, MUC2, MPG, ABCC3, HDAC4, TCN2, TYMS, DBF4, CASP3, SGPL1, GH2, EGF, CCND1, GPR39, IVL, AR, NT5E, LYZ, SMPD1, PHGDH, CDKN2A, MGST1, CCNA2, POLD1, NOS3, ABCB1, DHCR24, LDLR, HSD17B1, SOCS1, FBP1, LTC4S, CTSL, BIRC5, HRAS, PDHA1, TIMP2, P4HA1, TMPO, ARF6, CDKN1B, SLC31A1, SOX9, PLAU, RGN, CTSB, EZR, TIMP3, F7, SREBF1, SKP2, SCT, VDR, ADRB3, CXCL5, LMO4, CD163, MCTS1, ATF2, CTGF, SRC, P2RX4, TGFA, IL3, CYP7B1, ADRA1A, GRIN1, SRY, ODC12ADAM17, EGFR
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
EGFRYES30AR, BCL3, WWP1, NR3C2, TFAP2A, PGR, NFKB2, SP1, EGR1, PML, HDAC3, MTA1, BRCA1, WT1, VDR, HOXB7, JUN, TP53, RELA, LRRFIP1, NFKB1, STAT1, STAT3, YY1, YBX1, ESR1, JUNB, PPARG, CREBBP, TSG1010
ADAM17YES1SP10
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
EGFRADAM17No5TNFRSF1A, FBXO6, PTCH1, PDIA3, TGFA

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
EGFRADAM17Yesbinding, activation, expression17NOTCH1, NRG4, NRG3, NOTCH4, PRKCB, NRG2, TRAF6, UBC, ERBB2, IL8, TIMP3, PRKCA, HBEGF, NOTCH3, EGF, VEGFA, ERBB4

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Epithelial cell signaling in Helicobacter pylori infectionhsa051206.582ADAM17, EGFR

NET-GE enrichment

Term New enriched termICP valueGenes
Epithelial cell signaling in Helicobacter pylori infection (hsa05120) -6.580.028ADAM17, EGFR
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Signalling by NGFR-HSA-1665204.232ADAM17, EGFR
Diseases of signal transductionR-HSA-56632024.892ADAM17, EGFR
Immune SystemR-HSA-1682562.372ADAM17, EGFR
Cytokine Signaling in Immune systemR-HSA-12802153.742ADAM17, EGFR
Signal TransductionR-HSA-1625821.782ADAM17, EGFR
Signaling by ERBB4R-HSA-12363944.72ADAM17, EGFR
Signaling by EGFRR-HSA-1779294.592ADAM17, EGFR
DiseaseR-HSA-16436853.332ADAM17, EGFR

NET-GE enrichment

Term New enriched termICP valueGenes
Hedgehog ligand biogenesis (R-HSA-5358346) NEW6.980.013ADAM17, EGFR
Nuclear signaling by ERBB4 (R-HSA-1251985) NEW7.70.01ADAM17, EGFR
p75 NTR receptor-mediated signalling (R-HSA-193704) NEW6.590.044ADAM17, EGFR
Release of Hh-Np from the secreting cell (R-HSA-5362798) NEW9.980.0ADAM17, EGFR
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
protein complex binding (GO:0032403) 3.092ADAM17, EGFR
catalytic activity (GO:0003824) 1.052ADAM17, EGFR
macromolecular complex binding (GO:0044877) 2.612ADAM17, EGFR
binding (GO:0005488) 0.182ADAM17, EGFR
protein binding (GO:0005515) 0.462ADAM17, EGFR

NET-GE enrichment

Term New enriched termICP valueGenes
integrin binding (GO:0005178) NEW5.070.003ADAM17, EGFR
cell adhesion molecule binding (GO:0050839) NEW4.50.007ADAM17, EGFR
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
primary metabolic process (GO:0044238) 0.692ADAM17, EGFR
regulation of phosphate metabolic process (GO:0019220) 2.352ADAM17, EGFR
regulation of primary metabolic process (GO:0080090) 1.082ADAM17, EGFR
regulation of metabolic process (GO:0019222) 1.022ADAM17, EGFR
negative regulation of response to stimulus (GO:0048585) 2.522ADAM17, EGFR
positive regulation of response to stimulus (GO:0048584) 2.182ADAM17, EGFR
regulation of response to stimulus (GO:0048583) 1.542ADAM17, EGFR
signal transduction (GO:0007165) 1.282ADAM17, EGFR
cell surface receptor signaling pathway (GO:0007166) 2.092ADAM17, EGFR
enzyme linked receptor protein signaling pathway (GO:0007167) 3.242ADAM17, EGFR
transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) 3.542ADAM17, EGFR
positive regulation of cell cycle (GO:0045787) 3.942ADAM17, EGFR
negative regulation of signal transduction (GO:0009968) 2.752ADAM17, EGFR
regulation of signal transduction (GO:0009966) 1.842ADAM17, EGFR
positive regulation of signal transduction (GO:0009967) 2.52ADAM17, EGFR
animal organ development (GO:0048513) 2.532ADAM17, EGFR
positive regulation of molecular function (GO:0044093) 2.232ADAM17, EGFR
positive regulation of cell growth (GO:0030307) 4.732ADAM17, EGFR
positive regulation of biological process (GO:0048518) 1.22ADAM17, EGFR
negative regulation of biological process (GO:0048519) 1.332ADAM17, EGFR
regulation of cell proliferation (GO:0042127) 2.412ADAM17, EGFR
regulation of macromolecule metabolic process (GO:0060255) 1.082ADAM17, EGFR
regulation of protein kinase activity (GO:0045859) 3.152ADAM17, EGFR
epidermal growth factor receptor signaling pathway (GO:0007173) 5.722ADAM17, EGFR
response to organic substance (GO:0010033) 2.22ADAM17, EGFR
regulation of phosphorylation (GO:0042325) 2.52ADAM17, EGFR
positive regulation of phosphorylation (GO:0042327) 2.92ADAM17, EGFR
cell motility (GO:0048870) 3.022ADAM17, EGFR
protein metabolic process (GO:0019538) 1.452ADAM17, EGFR
regulation of peptidyl-tyrosine phosphorylation (GO:0050730) 4.352ADAM17, EGFR
regulation of cyclin-dependent protein kinase activity (GO:1904029) 5.212ADAM17, EGFR
regulation of mitotic cell cycle phase transition (GO:1901990) 4.232ADAM17, EGFR
positive regulation of metabolic process (GO:0009893) 1.742ADAM17, EGFR
positive regulation of kinase activity (GO:0033674) 3.542ADAM17, EGFR
movement of cell or subcellular component (GO:0006928) 2.612ADAM17, EGFR
positive regulation of protein serine/threonine kinase activity (GO:0071902) 4.062ADAM17, EGFR
regulation of ERBB signaling pathway (GO:1901184) 5.32ADAM17, EGFR
regulation of protein serine/threonine kinase activity (GO:0071900) 3.582ADAM17, EGFR
regulation of apoptotic process (GO:0042981) 2.52ADAM17, EGFR
regulation of biological process (GO:0050789) 0.452ADAM17, EGFR
cellular protein metabolic process (GO:0044267) 1.632ADAM17, EGFR
regulation of mitotic cell cycle (GO:0007346) 3.712ADAM17, EGFR
positive regulation of transferase activity (GO:0051347) 3.312ADAM17, EGFR
cellular macromolecule metabolic process (GO:0044260) 0.932ADAM17, EGFR
regulation of kinase activity (GO:0043549) 3.072ADAM17, EGFR
regulation of cellular component movement (GO:0051270) 3.082ADAM17, EGFR
positive regulation of cyclin-dependent protein kinase activity (GO:1904031) 6.152ADAM17, EGFR
biological regulation (GO:0065007) 0.392ADAM17, EGFR
positive regulation of catalytic activity (GO:0043085) 2.42ADAM17, EGFR
regulation of molecular function (GO:0065009) 1.782ADAM17, EGFR
cell migration (GO:0016477) 3.122ADAM17, EGFR
single organism cell adhesion (GO:0098602) 3.632ADAM17, EGFR
cell-cell adhesion (GO:0098609) 3.342ADAM17, EGFR
regulation of catalytic activity (GO:0050790) 1.972ADAM17, EGFR
regulation of cellular process (GO:0050794) 0.52ADAM17, EGFR
regulation of cell cycle phase transition (GO:1901987) 4.152ADAM17, EGFR
response to stress (GO:0006950) 1.82ADAM17, EGFR
metabolic process (GO:0008152) 0.582ADAM17, EGFR
positive regulation of macromolecule metabolic process (GO:0010604) 1.812ADAM17, EGFR
regulation of phosphorus metabolic process (GO:0051174) 2.352ADAM17, EGFR
response to stimulus (GO:0050896) 1.222ADAM17, EGFR
positive regulation of protein modification process (GO:0031401) 2.72ADAM17, EGFR
regulation of transferase activity (GO:0051338) 2.882ADAM17, EGFR
regulation of cell motility (GO:2000145) 3.162ADAM17, EGFR
positive regulation of cell motility (GO:2000147) 3.742ADAM17, EGFR
cellular developmental process (GO:0048869) 1.822ADAM17, EGFR
positive regulation of phosphorus metabolic process (GO:0010562) 2.782ADAM17, EGFR
regulation of protein metabolic process (GO:0051246) 1.932ADAM17, EGFR
regulation of cellular component organization (GO:0051128) 2.012ADAM17, EGFR
positive regulation of signaling (GO:0023056) 2.412ADAM17, EGFR
negative regulation of signaling (GO:0023057) 2.652ADAM17, EGFR
ERBB signaling pathway (GO:0038127) 5.362ADAM17, EGFR
regulation of signaling (GO:0023051) 1.722ADAM17, EGFR
positive regulation of cell communication (GO:0010647) 2.412ADAM17, EGFR
regulation of cell communication (GO:0010646) 1.732ADAM17, EGFR
single-organism process (GO:0044699) 0.482ADAM17, EGFR
response to endogenous stimulus (GO:0009719) 2.792ADAM17, EGFR
regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031657) 7.532ADAM17, EGFR
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031659) 7.652ADAM17, EGFR
regulation of cell cycle process (GO:0010564) 3.52ADAM17, EGFR
positive regulation of protein metabolic process (GO:0051247) 2.432ADAM17, EGFR
positive regulation of cellular protein metabolic process (GO:0032270) 2.492ADAM17, EGFR
regulation of protein modification process (GO:0031399) 2.322ADAM17, EGFR
biological adhesion (GO:0022610) 2.812ADAM17, EGFR
positive regulation of cell proliferation (GO:0008284) 3.012ADAM17, EGFR
response to oxygen-containing compound (GO:1901700) 2.572ADAM17, EGFR
positive regulation of cellular component movement (GO:0051272) 3.712ADAM17, EGFR
cellular process (GO:0009987) 0.262ADAM17, EGFR
regulation of cell growth (GO:0001558) 3.752ADAM17, EGFR
regulation of localization (GO:0032879) 1.942ADAM17, EGFR
regulation of cellular protein metabolic process (GO:0032268) 1.992ADAM17, EGFR
regulation of G1/S transition of mitotic cell cycle (GO:2000045) 4.812ADAM17, EGFR
macromolecule metabolic process (GO:0043170) 0.832ADAM17, EGFR
positive regulation of protein kinase activity (GO:0045860) 3.612ADAM17, EGFR
developmental process (GO:0032502) 1.362ADAM17, EGFR
single organismal cell-cell adhesion (GO:0016337) 3.692ADAM17, EGFR
positive regulation of growth (GO:0045927) 4.252ADAM17, EGFR
positive regulation of cellular metabolic process (GO:0031325) 1.812ADAM17, EGFR
regulation of cellular metabolic process (GO:0031323) 1.072ADAM17, EGFR
regulation of epidermal growth factor receptor signaling pathway (GO:0042058) 5.332ADAM17, EGFR
regulation of cell death (GO:0010941) 2.432ADAM17, EGFR
response to lipid (GO:0033993) 3.112ADAM17, EGFR
regulation of growth (GO:0040008) 3.262ADAM17, EGFR
organic substance metabolic process (GO:0071704) 0.632ADAM17, EGFR
regulation of programmed cell death (GO:0043067) 2.492ADAM17, EGFR
positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737) 6.22ADAM17, EGFR
positive regulation of cell migration (GO:0030335) 3.772ADAM17, EGFR
regulation of cell migration (GO:0030334) 3.232ADAM17, EGFR
positive regulation of phosphate metabolic process (GO:0045937) 2.782ADAM17, EGFR
single-organism developmental process (GO:0044767) 1.492ADAM17, EGFR
single-organism cellular process (GO:0044763) 0.652ADAM17, EGFR
cell adhesion (GO:0007155) 2.822ADAM17, EGFR
response to chemical (GO:0042221) 1.982ADAM17, EGFR
locomotion (GO:0040011) 2.912ADAM17, EGFR
response to abiotic stimulus (GO:0009628) 2.82ADAM17, EGFR
regulation of locomotion (GO:0040012) 3.122ADAM17, EGFR
positive regulation of locomotion (GO:0040017) 3.712ADAM17, EGFR
regulation of cell cycle (GO:0051726) 2.932ADAM17, EGFR
regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079) 5.262ADAM17, EGFR
anatomical structure development (GO:0048856) 1.582ADAM17, EGFR
cellular metabolic process (GO:0044237) 0.692ADAM17, EGFR
regulation of cell cycle G1/S phase transition (GO:1902806) 4.742ADAM17, EGFR
negative regulation of cell communication (GO:0010648) 2.662ADAM17, EGFR
regulation of protein phosphorylation (GO:0001932) 2.572ADAM17, EGFR
positive regulation of protein phosphorylation (GO:0001934) 2.952ADAM17, EGFR
negative regulation of cellular process (GO:0048523) 1.412ADAM17, EGFR
positive regulation of cellular process (GO:0048522) 1.32ADAM17, EGFR

NET-GE enrichment

Term New enriched termICP valueGenes
positive regulation of receptor activity (GO:2000273) NEW5.970.028ADAM17, EGFR
negative regulation of mitotic cell cycle (GO:0045930) NEW4.450.025ADAM17, EGFR
regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031657) -7.530.001ADAM17, EGFR
positive regulation of cell cycle (GO:0045787) -3.940.023ADAM17, EGFR
regulation of epidermal growth factor-activated receptor activity (GO:0007176) NEW6.590.012ADAM17, EGFR
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031659) -7.650.001ADAM17, EGFR
cellular response to glucocorticoid stimulus (GO:0071385) NEW5.740.032ADAM17, EGFR
cellular response to corticosteroid stimulus (GO:0071384) NEW5.670.036ADAM17, EGFR
regulation of epidermal growth factor receptor signaling pathway (GO:0042058) -5.330.008ADAM17, EGFR
positive regulation of ERBB signaling pathway (GO:1901186) NEW6.150.015ADAM17, EGFR
positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737) -6.20.001ADAM17, EGFR
positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) NEW7.330.002ADAM17, EGFR
positive regulation of protein tyrosine kinase activity (GO:0061098) NEW6.070.048ADAM17, EGFR
positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) NEW6.170.013ADAM17, EGFR
regulation of ERBB signaling pathway (GO:1901184) -5.30.008ADAM17, EGFR
JAK-STAT cascade (GO:0007259) NEW5.990.045ADAM17, EGFR
regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079) -5.260.013ADAM17, EGFR
cell adhesion mediated by integrin (GO:0033627) NEW7.240.001ADAM17, EGFR
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
plasma membrane region (GO:0098590) 2.972ADAM17, EGFR
intracellular organelle (GO:0043229) 0.512ADAM17, EGFR
cell-substrate adherens junction (GO:0005924) 3.832ADAM17, EGFR
focal adhesion (GO:0005925) 3.832ADAM17, EGFR
organelle (GO:0043226) 0.42ADAM17, EGFR
intrinsic component of membrane (GO:0031224) 1.132ADAM17, EGFR
cell-substrate junction (GO:0030055) 3.822ADAM17, EGFR
cytoplasm (GO:0005737) 1.012ADAM17, EGFR
integral component of membrane (GO:0016021) 1.142ADAM17, EGFR
membrane (GO:0016020) 0.682ADAM17, EGFR
cell junction (GO:0030054) 2.752ADAM17, EGFR
plasma membrane part (GO:0044459) 1.952ADAM17, EGFR
anchoring junction (GO:0070161) 3.612ADAM17, EGFR
cell surface (GO:0009986) 3.442ADAM17, EGFR
membrane region (GO:0098589) 3.952ADAM17, EGFR
adherens junction (GO:0005912) 3.662ADAM17, EGFR
plasma membrane (GO:0005886) 1.392ADAM17, EGFR
membrane raft (GO:0045121) 4.182ADAM17, EGFR
cell part (GO:0044464) 0.112ADAM17, EGFR
intracellular part (GO:0044424) 0.282ADAM17, EGFR
membrane part (GO:0044425) 0.952ADAM17, EGFR
membrane microdomain (GO:0098857) 4.172ADAM17, EGFR

NET-GE enrichment

Term New enriched termICP valueGenes
apical plasma membrane (GO:0016324) NEW4.130.009ADAM17, EGFR
plasma membrane region (GO:0098590) -2.970.027ADAM17, EGFR
cell surface (GO:0009986) -3.440.04ADAM17, EGFR
membrane raft (GO:0045121) -4.180.007ADAM17, EGFR